Microfluidic Modulation Spectroscopy (MMS) For Protein Therapeutic Drug Analysis

This application note provides an overview of RedShiftBio’s technology performance and capabilities within a new analyzer currently in late stages of development. A prototype analyzer was used to perform measurements of both commercially available proteins and proprietary proteins. Studies demonstrate significant increases in sensitivity, dynamic range, and utility for determination of protein similarity (fingerprinting), quantitation, protein secondary structure, and protein stability and aggregation through thermal and chemical denaturation methods.

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