Resources

Mutation-induced Structural Changes of a Bacterial Protein Detected by MMS

September 20, 2024

Structural Characterization of Antibody Drug Conjugates as Formulated and Under Multiple Conjugation Paradigms

August 30, 2024

Structural Characterization and Comparison of Temperature Stress on a Protein Library Across pH and Concentration using Microfluidic Modulation Spectroscopy

June 18, 2024

Assigning IR Absorption Bands for RNA Building Blocks Using Microfluidic Modulation Spectroscopy

May 13, 2024

Aurora TX Brochure

May 2, 2024

Microfluidic Modulation Spectroscopy: A Technology Overview with Peptide, Protein, and mRNA Examples

April 8, 2024

Structural Characterization of RNA and Detection of RNA-ligand Binding Using Microfluidic Modulation Spectroscopy

March 28, 2024

Characterization of Recombinant Human Lactoferrin Expressed in Komagataella Phaffii

February 29, 2024

Structural Comparison of the Matrix Metalloproteinase Proenzymes Using Microfluidic Modulation Spectroscopy

February 29, 2024

PODCAST: How Real Time Titer Measurement And Monitoring Is Advancing Bioproduction Across Multiple Applications

February 27, 2024

The Current Landscape of Monoclonal Antibody Production

February 22, 2024

E-Book: Monoclonal Antibody Manufacturing Trends, Challenges, and Analytical Solutions to Eliminate Bioprocessing Bottlenecks

February 22, 2024

How Real Time Titer Measurement And Monitoring Is Advancing Bioproduction Across Multiple Applications

February 6, 2024

Primary, Secondary, and Quaternary Structure Characterization of IgG1, IgG2, IgG3, and IgG4 Fc regions

February 6, 2024

Infographic: HaLCon Protein Analyzer: Purpose-built Liquid Chromatography System for Bioprocessing

January 9, 2024

Spinco Cutting Edge - January 2024

Spotlight on Aurora: One Drop Protein Characterization

January 9, 2024

bioRxiv

Characterization of Recombinant Human Lactoferrin Expressed in Komagataella Phaffii

January 3, 2024

Microfluidic Modulation Spectroscopy (MMS) for Monitoring Protein Structure During Re-Folding and Thermal Stress

December 21, 2023

Pushing boundaries in protein structure-function analysis: How MMS exceeds CD spectroscopy at in-situ detection and characterization of structural changes in proteins

December 12, 2023

Structural characterization of RNA and the spectral changes that accompany ligand binding, detected by MMS

December 6, 2023

Open Biology

The role of α-sheet structure in amyloidogenesis: characterization and implications

December 4, 2023

Structural Comparison of the Matrix Metalloproteinase Proenzymes Using Microfluidic Modulation Spectroscopy

November 30, 2023

MMS discovers ligand binding interaction in situ: The bile sensing system of Vibrio cholerae’s ToxRSp protein complex

November 13, 2023

Overcoming the Challenges of Monitoring Product Concentration at a CDMO

November 8, 2023

Advancing Biopharma Development With Novel Protein Refolding and Biophysical Characterization Techniques

November 7, 2023

Journal of Biomolecular Structure and Dynamics

Cefmetazole sodium as an allosteric effector that regulates the oxygen supply efficiency of adult hemoglobin

November 1, 2023

Automating Titer Measurement

October 23, 2023

Analytical Chemistry

Advancement of Microfluidic Modulation Spectroscopy as a Highly Sensitive Protein Characterization Technique for the Detection of Small Structural Changes

October 16, 2023

Lab + Life Scientist October 2023

Unravelling the Mysteries of Proteins: Meet Aurora, by RedShiftBio

October 10, 2023

Lab & Life Scientist

Advancing food science with Microfluidic Modulation Spectroscopy

October 3, 2023

Structural Comparison of the Kallikrein Proteins Using Microfluidic Modulation Spectroscopy

October 2, 2023

Structure, Stability, Similarity, and Stress Characterization of a commercial mAb and Two Biosimilar Drugs Using Microfluidic Modulation Spectroscopy (MMS)

September 28, 2023

Elife

Vibrio cholerae's ToxRS bile sensing system

August 29, 2023

Conquering Bioprocessing Challenges with Efficient Protein Titer Measurement

August 14, 2023

HaLCon, a Fit for Purpose, Platform Method for Rapid Antibody Concentration Measurements from Cell-Free Culture Media

August 14, 2023

Overcoming the Challenges of Product Concentration Monitoring at a CDMO

August 14, 2023

HaLCon, a Fit for Purpose, Platform Method for Rapid Antibody Concentration

July 27, 2023

Subtle Changes in Protein Structure Lead to Dramatic Changes in Function: Next-Generation Structural Characterization with Microfluidic Modulation Spectroscopy

July 13, 2023

Aurora Brochure

June 14, 2023

Microfluidic Modulation Spectroscopy: A Technology Platform for Ultra- sensitive Analysis of Proteins, from Structure to Activity

June 8, 2023

Behind the App Note: How secondary structure relates to enzyme activity: The structural differences between α-chymotrypsin and its inactive precursor chymotrypsinogen determined with Microfluidic Modulation Spectroscopy (MMS)

June 6, 2023

Structural Characterization and Temperature and Pressure Stress Comparison on Ovalbumin using MMS

May 12, 2023

HaLCon Product Brochure

May 11, 2023

Microfluidic Modulation Spectroscopy: A Technology Platform for Ultra- sensitive Analysis of Proteins, from Structure to Activity

May 3, 2023

Structure, Stability, Similarity, and Stress Characterization of a Commercial mAb Therapeutic and Two Biosimilar Drugs Using Microfluidic Modulation Spectroscopy (MMS)

April 25, 2023

Application of Microfluidic Modulation Spectroscopy (MMS) for Characterizing the Secondary Structure of Mixed Food Protein Complexes

April 10, 2023

A Structural Characterization of a Monoclonal Antibody Therapeutic as Formulated and Under Multiple Conjugation Paradigms

March 29, 2023

How secondary structure relates to enzyme activity: The structural differences between α-chymotrypsin and its inactive precursor chymotrypsinogen determined with Microfluidic Modulation Spectroscopy (MMS)

March 23, 2023

α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease

March 23, 2023

Secondary structure characterization of mixed food protein complexes using microfluidic modulation spectroscopy (MMS)

March 3, 2023

Rapid and Accurate Determination of the Higher Order Structure of a Library of Proteins Using Microfluidic Modulation Spectroscopy

March 3, 2023

Behind the App Note: Assessment of Protein Hydration, Surface Hydrophobicity, and Structure in One Single Automated Measurement

February 9, 2023

Lead Optimization using Microfluidic Modulation Spectroscopy

February 1, 2023

Characterization of Three USP Reference Standards using Microfluidic Modulation Spectroscopy

January 20, 2023

Behind the App Note: MMS as a Non-Destructive Structural CharacterizationTechnique: A Case Study Using BSA

January 4, 2023

Assessment of Protein Hydration, Surface Hydrophobicity, and Structure in One Single Automated Measurement

December 6, 2022

Behind the App Note: Detection of Pressure-Induced Protein Aggregation Using Microfluidic Modulation Spectroscopy (MMS)

November 30, 2022

PEGS Europe 2022: Measuring Change in Secondary Structure and Oligomeric State for a mAb in Stress and In-Process Testing with MMS and SEC

November 9, 2022

Sciex MasterClass On-Demand: Measuring Changes in Protein Structure with Microfluidic Modulation Spectroscopy

November 1, 2022

Microfluidic Modulation Spectroscopy as a Non-Destructive Structural Characterization Technique: A Case Study Using Bovine Serum Albumin

October 26, 2022

Protein Therapeutics: Understanding the Biophysical Characterization Toolbox

October 3, 2022

Characterizing Amyloid-Forming Immunoglobulin G Light and Variable Chains Using Microfluidic Modulation Spectroscopy

September 12, 2022

Behind the App Note: Benchmarking the RedShiftBio Apollo MMS System Performance Versus the First-Generation AQS3®pro

September 12, 2022

Benchmarking the RedShiftBio Apollo MMS System Performance Versus the First-Generation AQS3®pro

August 24, 2022

Characterizing Amyloid-Forming IgG Light and Variable Chains Using Microfluidic Modulation Spectroscopy

August 23, 2022

Characterizing Amyloid-Forming Immunoglobulin G Light and Variable Chains Using Microfluidic Modulation Spectroscopy

August 18, 2022

Behind the App Note: Protein Dilution and Subsequent Concentration Provide a Well-Matched Sample/Buffer Pair for High-Resolution MMS

August 10, 2022

Higher-Order Structure Assessment of a Protein Library by Microfluidic Modulation Spectroscopy (MMS)

August 1, 2022

Introducing HaLCon: Real Time Titer Measurement for Bioprocessing

July 29, 2022

Protein Dilution and Subsequent Concentration Provide a Well-Matched Sample/Buffer Pair for High-Resolution MMS

July 20, 2022

Behind the App Note: Measuring Buffer-induced Structural Changes in an Alpha-helix Rich Enzyme

June 16, 2022

Measuring Buffer-Induced Structural Changes in a Beta-sheet Rich Protein using MMS

June 9, 2022

Advancing Structural Characterization of Therapeutic Proteins with Microfluidic Modulation Spectroscopy

June 8, 2022

The Journal of Physical Chemistry B

High-Pressure, Low-Temperature Induced Unfolding and Aggregation of Monoclonal Antibodies: Role of the Fc and Fab Fragments

May 25, 2022

Using MMS to Measure Buffer-Induced Structural Changes in an Alpha-helix Rich Enzyme

May 24, 2022

Apollo Launch Webinar

May 6, 2022

A New Tool for your Biophysical Toolkit, MMS: Automated, IR-Based Protein Structural Analysis for Stability & Formulation Testing

May 2, 2022

Apollo Product Brochure

May 2, 2022

Characterization of Protein Secondary Structure and Aggregation Utilizing Microfluidic Modulation Spectroscopy

April 5, 2022

Higher Order Structure Determination of a Highly Pigmented Protein using Microfluidic Modulation Spectroscopy

March 21, 2022

Biologics UK 2022: Insights into Predicting Aggregation and Particle Formation Behaviour During Early Formulation Screening: The Role of Microfluidic Modulation Spectroscopy

March 12, 2022

Analytical Biochemistry

Advancing Secondary Structure Characterization of Monoclonal Antibodies using Microfluidic Modulation Spectroscopy

February 22, 2022

International Journal of Biological Macromolecules

Progress in Infrared Spectroscopy as an Efﬁcient Tool for Predicting Protein Secondary Structure

February 18, 2022

Microfluidic Modulation Spectroscopy as a Non-Destructive Structural Characterization Technique

February 15, 2022

Using Microfluidic Modulation Spectroscopy for Quality Assurance of Biologic Drugs: Five Applications to Remove Risk and Enable Better, Faster Decision-Making

January 18, 2022

PepTalk 2022 Presentation: AQS³pro and Microfluidic Modulation Spectroscopy - Accurate, Sensitive, and Reproducible Secondary Structure Measurements for Biophysical Molecule Characterization

December 20, 2021

mAbs

Quality Comparability Assessment of a SARS-CoV-2-neutralizing Antibody across Transient, Mini-pool-derived and Single-clone CHO Cells

December 3, 2021

Detecting Partial Unfolding of Hen Egg White Lysozyme in 2M Guanidine Hydrochloride Solution using Microfluidic Modulation Spectroscopy (MMS)

November 4, 2021

PEGS Europe 2021: Insights into predicting aggregation & particle formation behaviour during early formulation screening: The role of MMS

November 3, 2021

AQS³®pro Product Demonstration

July 29, 2021

Biosimilar Structural Comparison of Commercially Sourced Reference Standards by MMS Rapidly Detects Subtle but Critical Differences to Correctly Predict Activity for Use in an ELISA Product

July 1, 2021

Biopharm International

E-book: Improving IR Spectroscopy as a Tool for Biopharmaceutical Analysis

June 24, 2021

Biosimilar Comparison and Accelerated Stability Predictions Based on <2% Secondary Structure Differences Using Microfluidic Modulation Spectroscopy (MMS)

May 12, 2021

Genetic Engineering News

Automated High-throughput Infrared Spectroscopy for Secondary Structure Analysis of Protein Biopharmaceuticals

May 7, 2021

Virulence

Staphylococcus aureus N-terminus formylated δ-toxin tends to form amyloid fibrils, while the deformylated δ-toxin tends to form functional oligomer complexes

May 4, 2021

Pharmaceutical Technology

Focusing on Accelerated Formulation Strategies - PharmTech.com

April 29, 2021

Microfluidic Modulation Spectroscopy of a Biotherapeutic at Low to High Concentrations without Interference from Formulation Excipients

April 8, 2021

LabRoots

Webinar: Physicochemical Characterization of Antibody-Drug Conjugates

April 8, 2021