Adding Microfluidic Modulation Spectroscopy to your Toolbox: A Deeper Dive into Protein Characterization for Drug Discovery

Abstract

This video highlights a featured presentation from the RedShiftBio symposium, focusing on Pfizer's contributions.  Alison Varghese discussed her research on protein and structure, enabled by Microfluidic Modulation Spectroscopy (MMS) technology. Her presentation explored how MMS addresses scientific challenges and its critical role in biomolecular structural characterization for therapeutic development.

Expanding on these findings, the data underscores the superior quantitative capabilities of AuroraTX when compared to traditional UV methods while also providing invaluable insights into high-order protein structures, temperature-induced effects on soluble proteins, the influence of small molecule binding, the analysis of complex protein formations, and the confirmation of ligand binding to membrane proteins with detergents.

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