Microfluidic Modulation Spectroscopy: A Technology Overview with Peptide, Protein, and mRNA Examples

As presented at Formulation and Delivery UK 2024, Microfluidic Modulation Spectroscopy (MMS) is a revolution in IR spectroscopy, providing 30x greater sensitivity than traditional systems, using only a 50µl sample on a fully-automated platform. Here, Dr. Patrick King describes the technology and provides examples of peptide, protein, RNA, and oligonucleotide experiments.

Viewers will learn about the fundamentals of MMS, including a deep dive into the benefits of thermal ramping, a brand-new platform feature. MMS has emerged as a leader in protein characterization techniques and assessment of RNA stability and RNA purity in the context of the development of nucleic acid therapeutics. Learn more about how MMS is used for protein characterization, peptide characterization, and RNA characterization, including analysis of RNA base pairing and changes to due ligand binding.